Global Health and the Future Role of the United States


Introduction

Global Health and the Future Role of the United States, released in Spring 2017 by the National Academies of Sciences, Engineering, and Medicine, assesses U.S. investments in global health. Using the same rigor that the National Academies applied in advising U.S. policy for more than 150 years, a committee of experts from across the global health field reached consensus on why and how to continue America’s commitment to global health. The report culminates in 14 recommendations to guide action in improving the health of the world’s population.

The Legacy of U.S. Leadership in Global Health

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The data show that foreign assistance directed toward health is a sound investment.

20x In addition to saving millions of lives, returns on investment in health can exceed costs by up to 20 times in some countries.

Investing in global health also serves to protect the American people from pandemics, and it can also spur economic growth in those countries, as shown by 11 of the top 15 U.S. trading partners being former recipients of foreign aid. This summary is a resource for policymakers and other critical stakeholders on areas to prioritize within global health and how to make investments that scale.

11/15
top U.S. trading partners are former recipients of foreign aid

Global Health Security Is National Security

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Stakeholders

The National Academies report recommendations are aimed at the following groups.

U.S. Congress

U.S. Centers for Disease Control and Prevention

U.S. Department of Health
and Human Services

National Institutes
of Health

U.S. Agency for
International Development

Office of Management
and Budget

PEPFAR
(U.S. Department of State)

Presidential Administration

U.S. Department
of Agriculture

U.S. Department
of Defense

U.S. Department
of State

Nongovernmental Organizations

U.S. Food and Drug Administration

Biomedical Advanced Research and Development Authority

U.S. Department of
the Treasury


Recommendations

Securing Against Global Threats

In the last 10 years, outbreaks of potentially pandemic influenza, MERS-CoV, Ebola, and Zika have threatened populations around the world. In each case, global and national responses, including those of the United States, have been reactionary, uncoordinated, ineffective, and highly costly. Additionally, HIV/AIDS, tuberculosis (TB), and malaria continue to pose immediate and longer-term global health threats and require continued attention. Absent the establishment of fundamental public health protections and preparedness capabilities at home and abroad, the world will never be ready to prevent, detect, and respond to such outbreaks.

Improve International Emergency Response Coordination

Improve International Emergency Response Coordination

The presidential administration should create a coordinating body for international public health emergency response that is accountable for international and domestic actions and oversees preparedness for and responses to global health security threats.

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7 months


U.S. agencies had to wait for seven months for funding to respond to the Zika outbreak, threatening the safety of the American people and weakening other health capabilities.

Combat Antimicrobial Resistance

Combat Antimicrobial Resistance

Relevant agencies should continue to invest in national capabilities and accelerate the development of international capabilities to detect, monitor, report, and combat antibiotic resistance.

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10 million lives


The current rate of antimicrobial resistance is projected to result in a loss of 10 million lives per year and a cumulative loss of $100 trillion in global economic output by 2050. Combating resistance could mitigate these losses, maintain the integrity of treatment, and protect the progress achieved in reducing the burden of critical infectious diseases.

Build Public Health Capacity in Low- and Middle-Income Countries

Build Public Health Capacity in Low- and Middle-Income Countries

Relevant agencies should expand training and information exchange efforts to increase the capacity of low- and middle-income countries to respond to both public health emergencies and acute mass casualty disasters.

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75-80 percent


The United States currently imports 75–80 percent of the raw materials for drugs meant for the U.S. domestic market, which increases susceptibility to the effects of a public health emergency should an outbreak occur in an exporting country.

Envision the Next Generation of PEPFAR

Envision the Next Generation of PEPFAR

Congress should fund the President’s Emergency Plan for AIDS Relief (PEPFAR) at current levels, and allow for more flexibility within the PEPFAR program by continuing to relax specific funding targets for all program areas.

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13 percent


13 percent higher employment rates were found among men in PEPFAR countries than in non-PEPFAR countries.

Confront the Threat of Tuberculosis

Confront the Threat of Tuberculosis

Relevant agencies should conduct a thorough global threat assessment of rising tuberculosis (TB) levels, including multi- drug-resistant TB and extensively drug-resistant TB. They should then execute a plan of action, including governance structure and priority activities, for developing and investing in new diagnostics, drugs, vaccines, and delivery systems.

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100x more expensive


Treating drug-resistant tuberculosis can be 100x more expensive than treating non-resistant tuberculosis.

Sustain Progress Toward Malaria Elimination

Sustain Progress Toward Malaria Elimination

Relevant agencies should continue their commitment to the fight against malaria through the President’s Malaria Initiative and collaborative work with all partners toward elimination of the disease.

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48 percent


Since its creation, the President's Malaria Initiative has reduced malaria mortality by 48% in focus countries.

Enhancing Productivity & Economic Growth

The general health and well-being of other countries, including their burden of noncommunicable diseases such as cardiovascular disease and cancer, at first glance may not appear to be the top priority of donor countries such as the United States. However, investing in countries’ prosperity and stability can result in greater order and predictability in the world, as well as promote U.S. health and prosperity and create more reliable and durable global partners.

Improve Survival in Women and Children

Improve Survival in Women and Children

Congress should increase funding for USAID to augment the agency’s investments in ending preventable maternal and child mortality, defined as global maternal mortality rates of fewer than 70 deaths per 100,000 live births by 2020 and fewer than 25 child deaths per 1,000 live births by 2030.

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6 million children


More than 6 million children and 300,000 mothers die each year due to largely preventable causes.

Ensure Healthy and Productive Lives for Women and Children

Ensure Healthy and Productive Lives for Women and Children

Relevant agencies, their implementing partners, and other funders should support and incorporate proven, cost-effective interventions into their existing programs for ensuring that all children reach their developmental potential and become healthy, productive adults.

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25 percent


Early childhood interventions increase labor market participation, earnings, and economic growth, generating returns of up to 25 percent.

Promote Cardiovascular Health and Prevent Cancer

Promote Cardiovascular Health and Prevent Cancer

Relevant agencies, through their country offices, should provide seed funding to facilitate the mobilization and involvement of the private sector in addressing cardiovascular disease and cancer at the country level.

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$100-$200 billion


Investing in cancer care and control could result in millions of avoidable deaths, achieving between $100 and $200 billion in global economic savings.

Maximizing Returns on Investment

To have the greatest effect in the above priority areas, the committee identified three cross-cutting areas for action to maximize the returns on investments, achieve better health outcomes, and use funding more effectively:

1. Catalyze innovation through both the accelerated development of medical products and integrated digital health infrastructure;

2. Employ more nimble and flexible financing mechanisms to leverage new partners and funders in global health; and

3. Maintain U.S. status and influence as a world leader in global health while adhering to evidence-based science and economics, measurement, and accountability. Achieving true improvements in global health will require changing the way global health business is conducted to better enable innovation.

Accelerate the Development of Medical Products

Accelerate the Development of Medical Products

Relevant agencies should invest in a targeted effort to reduce the costs and risks of developing, licensing, and introducing vaccines, therapeutics, diagnostics, and devices needed to address global health priorities. This can be accomplished by enabling innovative approaches for trial design, streamlining regulation, ensuring production capacity, creating market incentives, and building international capacity for research and development.

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15 years


The average time to develop a new drug and enter the market is 15 years and the average cost is $2.5 billion. Between 2000 and 2011, only 4% of new products were targeted at neglected diseases.

Improve Digital Health Infrastructure

Improve Digital Health Infrastructure

Relevant agencies of the U.S. government should convene an international group of public and private stakeholders to create a common digital health framework that addresses country-level needs ranging from integrated care to research and development.

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25 percent


In 2015, 25 percent of the people in Africa and 58 percent in Asia had an internet connection, along with even higher access to mobile phones, paving the way for a truly global digital health network.

Transition Investments Toward Global Public Goods

Transition Investments Toward Global Public Goods

Relevant agencies should systematically assess their approach to global health funding with an eye toward making long-term investments in high-impact, country-level programs.

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$50 billion


US investments in the Global Polio Eradication Initiative are expected to generate returns of as much as $50 billion by 2035.

Optimize Resources Through Smart Financing

Optimize Resources Through Smart Financing

Relevant agencies should expand efforts to complement direct bilateral support for health with financing mechanisms that include results-based financing; risk sharing; and attracting funding from private investment, recipient governments, and other donors.

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72 percent


Investing in health makes business sense. A mining company in Ghana implemented malaria controls that led to a 72% decrease in disease burden, saving the company roughly $600,000 per year.

Commit to Continued Global Health Leadership

Commit to Continued Global Health Leadership

To protect itself from global threats, benefit from successes achieved in global health programs, and maintain a strong research and development pipeline, the United States should commit to maintaining its leadership in global health and actively participating in global health governance, coordination, and collaboration.

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30 percent


The United States needs a global health workforce. Because of system limitations there is a standing vacancy rate of more than 30% for overseas positions within the Department of Health and Human Services.


Conclusion

The health and well-being of other countries directly and indirectly affect the health, safety, and economic security of Americans. The United States must preserve and extend its legacy as a global leader, partner, and innovator in global health through forward-looking policies, a long-term vision, country and international partnerships, and, most importantly, continued investment.

We hope that this interactive breakdown of the National Academies report serves as a useful resource for policymakers as they consider how best to make investments to safeguard the health and security of all U.S. citizens through ensuring a sustainable and thriving global population.

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